Scenario 4:

A multi-centre, international, open 2x2 factorial randomised controlled trial of aspirin and heparin in acute ischaemic stroke, with an additional randomisation of dose in 2 arms.

A multi-centre, international, open 2x2 factorial randomised controlled trial of aspirin and heparin in acute ischaemic stroke, with an additional randomisation of dose in 2 arms.

Click on the resource below to see details of the monitoring procedures that are appropriate for this trial.